The Drug-Induced Respiratory Disease Website

Chemotherapy (antineoplastic) - Chemo agents

Left ventricular dysfunction/failure

De novo chronic, progressive or acute LV dysfunction/failure. May result from myocarditis or eosinophilic myocarditis. May cause congestive heart failure and/or pulmonary edema (see under II). Hypertension may be present. Symptoms range from worsening of preexisting LVF to acute cardiogenic pulmonary edema, shock or cardiopulmonary arrest. See also pulmonary edema under IId, and XIId, XIIf. Review at PMID 10193711, 16808550, 18083403, 21930637

Publications

Inui T, Kohno H, Matsuura K, Ueda H, Tamura Y, Watanabe M, Inage Y, Yakita Y, Matsumiya G

A case of left ventricular assist device application for chemotherapy-related cardiomyopathy caused by trastuzumab and anthracycline.

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2020 Sep;23;270-274 — 2020 Sep — 270-274

Yuki D, Okura Y, Takayama T, Kawasaki T, Kanbayashi C, Sato N

A case of chemoradiotherapy-associated cardiotoxicity that developed into acute heart failure with progressive subendocardial fibrosis.

Journal of cardiology cases 2014 Sep;10;115-120 — 2014 Sep — 115-120