Philippe Camus, M.D.

Dijon, France

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The Drug-Induced Respiratory Disease Website

Marijuana, cannabis (haschish, hash, bang, dab)

Some adverse effects of marijuana may overlap with those of tobacco smoke. Not all studies confirmed whether marijuana per se is harmful to the airways (PMID 29629404). Variation in cannabis/marijuana/haschich potency, concentration (e.g. resin, hash oil), contamination with fungi (PMID 6348548) and possible adulteration should be considered (PMID:18494838). Reviews at PMID 24831571, 24897085, 25996274, 26935046, 29629404, 29971337. Some users vaporize cannabis using electronic cigarette devices (PMID 30835796)

I - Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a

Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
I.j

Asystole

III - Myocardial ischemia - Coronary artery disease

III.a

Coronary artery disease (acute) - Myocardial ischemia/infarction
III.c

Coronary vasospasm - Vasospastic angina
III.e

Coronary artery dissection

IV - Heart block (bundle branch-, AV-block)

IV.a

Heart block (bundle branch- or AV-)

V - Myocarditis

V.a

Myocarditis (can be fulminate/fulminant)

XII - Pericardial involvement

XII.b

Pericardial effusion (w/wo tamponade)

XIV - Pleural involvement

XIV.a

Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV.f

Pneumothorax
XIV.l

Pneumothorax, bilateral

XV - Chest pain

XV.a

Chest pain (acute or subacute), lone or prominent

XVI - Hemorrhage - Bleeding - Hematoma(s)

XVI.e

Alveolar hemorrhage (AH), diffuse AH (DAH)
XVI.i

Hemoptysis

XXI - Mediastinal involvement/injury

XXI.c

Pneumomediastinum

XXII - Acute respiratory/cardiorespiratory failure

XXII.b

Acute lung injury - ARDS
XXII.e

Respiratory failure from ventilatory depression (of neuromuscular cause or causes)

XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b

Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV.c

Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXIV.d

Acute eosinophilic pneumonia (AEP)
XXIV.k

Pulmonary infiltrates
XXIV.y

Exogenous lipoid pneumonia (subacute, acute)
XXIV.ad

Pulmonary alveolar proteinosis (PAP)
XXIV.ae

Pneumoconiosis (silicosis, talcosis...)
XXIV.af

Hypersensitivity pneumonitis pattern

XXIX - Small airway involvement

XXIX.d

Cough (lone)

XXXVI - Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f

Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

XXXVIII - Miscellaneous - Varia

XXXVIII.e

Sniffing death - Death from inhalation of compound