The Drug-Induced Respiratory Disease Website

I - Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a

Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

1

Evidence level

low

I.g

QTc prolongation

1

Evidence level

low

I.i

Torsades de pointe

1

Evidence level

low

II - Myocardial dysfunction - Heart failure

II.a

Left ventricular dysfunction/failure

1

Evidence level

low

IV - Heart block (bundle branch-, AV-block)

IV.a

Heart block (bundle branch- or AV-)

1

Evidence level

low

VI - Cardiomyopathy

VI.a

Cardiomyopathy (acute, subacute, chronic)

2

Evidence level

possible

XI - Pulmonary vasculopathies

XI.a

Pulmonary arterial hypertension

1

Evidence level

low

XXIX - Small airway involvement

XXIX.a

Bronchospasm - Wheezing - Asthma

1

Evidence level

low

XXXIII - Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)

XXXIII.e

Path: Lysosomal storage cardiomyopathy/cardiotoxicity

1

Evidence level

low