The Drug-Induced Respiratory Disease Website

Pacemaker leads - Implantable cardiac devices

Including but not limited to implantable defibrillators. Complications may develop with insertion or later

Hemopericardium - Bloody pericardial effusion

Pulmonary embolism - Venous thrombosis/thrombo-embolism

Hemothorax - Serosanguineous pleural effusion

Pneumothorax

Perforation of the heart - Cardiac rupture

Venous thoracic outlet syndrome

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

No activity has been recorded yet.