The Drug-Induced Respiratory Disease Website

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.e Bradycardia

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XIV. Pleural involvement

XIV.f Pneumothorax

XV. Chest pain

XV.d Chest tightness

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.h Coagulopathy

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.i Hemoptysis

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.m BAL: Gross or microscopic bleeding/hemorrhage

XXI. Mediastinal involvement/injury

XXI.c Pneumomediastinum

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXII. Acute respiratory/cardiorespiratory failure

XXII.c Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO

XXIII. Hemoglobinopathies (acquired, reversible)

XXIII.a Methemoglobinemia

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXVII. Dyspnea, lone

XXVII.a Dyspnea, unexplained otherwise

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXIX. Small airway involvement

XXIX.c Severe or catastrophic bronchospasm or asthma attack (can be fatal)

XXIX. Small airway involvement

XXIX.f Deterioration/exacerbation of preexisting asthma or COPD

XXX. Imaging features

XXX.e Imaging: An area or areas of consolidation

XXX. Imaging features

XXX.f Imaging: Alveolar opacities or haze with a batwing or butterfly distribution

XXX. Imaging features

XXX.l Imaging: Ground-glass opacities / GGO shadowing

XXXI. Eye catchers

XXXI.e Eye catcher: A batwing or butterfly pattern on chest imaging

XXXIII. Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)

XXXIII.k Path: Alveolar hemorrhage

XXXIV. Infections

XXXIV.b Respiratory tract infection incl. pneumonia

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.p Multisystem/systemic inflammatory response/syndrome

XXXVIII. Miscellaneous - Varia

XXXVIII.c Antiphospholipid antibodies w/wo the APL syndrome