The Drug-Induced Respiratory Disease Website

XII. Pericardial involvement

XII.c Hemopericardium - Bloody pericardial effusion

XIV. Pleural involvement

XIV.e Hemothorax - Serosanguineous pleural effusion

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.a Hemomediastinum - Mediastinal hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.b Pulmonary hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.d Retropharyngeal hematoma (may cause UAO)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.i Hemoptysis

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.k Vocal cord hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.l Thoracic epidural or spinal hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.m BAL: Gross or microscopic bleeding/hemorrhage

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.n Rectus abdominis sheath hematoma

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.o Epistaxis

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.i Progression, acceleration or exacerbation of preexisting ILD/fibrosis

XXVIII. Large airway involvement

XXVIII.a Angioedema (may cause UAO, asphyxia and death)

XXVIII. Large airway involvement

XXVIII.i Tongue involvement (edema, glossitis, hematoma)

XXXII. Esophageal pathology

XXXII.a Esophageal hematoma (may cause chest pain and/or tracheal compression)

XXXVII. Veterinary medicine and pathology

XXXVII.e Veterinary: (Peri-) tracheal/retropharyngeal hemorrhage

XXXVIII. Miscellaneous - Varia

XXXVIII.l Calcification of tracheobronchial cartilaginous rings

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.e Bradycardia

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XIV. Pleural involvement

XIV.f Pneumothorax

XV. Chest pain

XV.d Chest tightness

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.h Coagulopathy

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.i Hemoptysis

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.m BAL: Gross or microscopic bleeding/hemorrhage

XXI. Mediastinal involvement/injury

XXI.c Pneumomediastinum

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXII. Acute respiratory/cardiorespiratory failure

XXII.c Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO

XXIII. Hemoglobinopathies (acquired, reversible)

XXIII.a Methemoglobinemia

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXVII. Dyspnea, lone

XXVII.a Dyspnea, unexplained otherwise

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXIX. Small airway involvement

XXIX.c Severe or catastrophic bronchospasm or asthma attack (can be fatal)

XXIX. Small airway involvement

XXIX.f Deterioration/exacerbation of preexisting asthma or COPD

XXX. Imaging features

XXX.e Imaging: An area or areas of consolidation

XXX. Imaging features

XXX.f Imaging: Alveolar opacities or haze with a batwing or butterfly distribution

XXX. Imaging features

XXX.l Imaging: Ground-glass opacities / GGO shadowing

XXXI. Eye catchers

XXXI.e Eye catcher: A batwing or butterfly pattern on chest imaging

XXXIII. Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)

XXXIII.k Path: Alveolar hemorrhage

XXXIV. Infections

XXXIV.b Respiratory tract infection incl. pneumonia

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.p Multisystem/systemic inflammatory response/syndrome

XXXVIII. Miscellaneous - Varia

XXXVIII.c Antiphospholipid antibodies w/wo the APL syndrome