VIII.a
VIII - Valvular heart disease
Valvular heart disease and/or dysfunction
Last update 17/06/2026
See PMID 19683643, 20716786, 23769407, 26833208
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The Drug-Induced Respiratory Disease Website
Causative drugs
4
VIII.a
VIII. Valvular heart disease
VIII.a Valvular heart disease and/or dysfunction
XI.a
XI. Pulmonary vasculopathies
XI.a Pulmonary arterial hypertension
XIV.a
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV.h
XIV. Pleural involvement
XIV.h Pleural thickening - Fibrothorax
I.a
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
I.b
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.b Atrial fibrillation
II.a
II. Myocardial dysfunction - Heart failure
II.a Left ventricular dysfunction/failure
III.a
III. Myocardial ischemia - Coronary artery disease
III.a Coronary artery disease (acute) - Myocardial ischemia/infarction
IV.a
IV. Heart block (bundle branch-, AV-block)
IV.a Heart block (bundle branch- or AV-)
VI.a
VI. Cardiomyopathy
VI.a Cardiomyopathy (acute, subacute, chronic)
VI.c
VI. Cardiomyopathy
VI.c Takotsubo (stress) cardiomyopathy
VIII.a
VIII. Valvular heart disease
VIII.a Valvular heart disease and/or dysfunction
XI.a
XI. Pulmonary vasculopathies
XI.a Pulmonary arterial hypertension
XI.i
XI. Pulmonary vasculopathies
XI.i Pulmonary veno-occlusive disease
XII.b
XII. Pericardial involvement
XII.b Pericardial effusion (w/wo tamponade)
XXVI.a
XXVI. Neuromuscular dysfunction
XXVI.a Phrenic nerve injury - Hemi- or bilateral diaphragmatic paralysis
XXXVI.f
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)
XXXVIII.k
XXXVIII. Miscellaneous - Varia
XXXVIII.k Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)
II.a
II. Myocardial dysfunction - Heart failure
II.a Left ventricular dysfunction/failure
V.a
V. Myocarditis
V.a Myocarditis (can be fulminate/fulminant)
VIII.a
VIII. Valvular heart disease
VIII.a Valvular heart disease and/or dysfunction
X.a
X. Pulmonary edema
X.a Pulmonary edema, cardiogenic
X.b
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XVI.c
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.c Hematoma of/around central airway wall potentially causing UAO
XXII.b
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXXVIII.a
XXXVIII. Miscellaneous - Varia
XXXVIII.a Upper airway obstruction other than angioedema or hematoma