I.e
I - Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
Bradycardia
Last update 17/06/2026
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16
I.e
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.e Bradycardia
VII.a
VII. Cardiotoxicity
VII.a ‘Cardiotoxicity’
XXII.b
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV.a
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
I.e
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.e Bradycardia
I.l
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.l Cardiac- cardiorespiratory/pulmonary arrest
II.d
II. Myocardial dysfunction - Heart failure
II.d Cardiovascular collapse - Cardiogenic shock - Hypotension
III.c
III. Myocardial ischemia - Coronary artery disease
III.c Coronary vasospasm - Vasospastic angina
I.a
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
I.e
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.e Bradycardia
II.a
II. Myocardial dysfunction - Heart failure
II.a Left ventricular dysfunction/failure
XIV.a
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV.f
XIV. Pleural involvement
XIV.f Pneumothorax
XV.d
XV. Chest pain
XV.d Chest tightness
XVI.e
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XVI.h
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.h Coagulopathy
XVI.i
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.i Hemoptysis
XVI.m
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.m BAL: Gross or microscopic bleeding/hemorrhage
XXI.c
XXI. Mediastinal involvement/injury
XXI.c Pneumomediastinum
XXII.b
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXII.c
XXII. Acute respiratory/cardiorespiratory failure
XXII.c Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO
XXIII.a
XXIII. Hemoglobinopathies (acquired, reversible)
XXIII.a Methemoglobinemia
XXIV.a
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV.b
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV.c
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXVII.a
XXVII. Dyspnea, lone
XXVII.a Dyspnea, unexplained otherwise
XXIX.a
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXIX.c
XXIX. Small airway involvement
XXIX.c Severe or catastrophic bronchospasm or asthma attack (can be fatal)
XXIX.f
XXIX. Small airway involvement
XXIX.f Deterioration/exacerbation of preexisting asthma or COPD
XXX.e
XXX. Imaging features
XXX.e Imaging: An area or areas of consolidation
XXX.f
XXX. Imaging features
XXX.f Imaging: Alveolar opacities or haze with a batwing or butterfly distribution
XXX.l
XXX. Imaging features
XXX.l Imaging: Ground-glass opacities / GGO shadowing
XXXI.e
XXXI. Eye catchers
XXXI.e Eye catcher: A batwing or butterfly pattern on chest imaging
XXXIII.k
XXXIII. Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)
XXXIII.k Path: Alveolar hemorrhage
XXXIV.b
XXXIV. Infections
XXXIV.b Respiratory tract infection incl. pneumonia
XXXVI.p
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.p Multisystem/systemic inflammatory response/syndrome
XXXVIII.c
XXXVIII. Miscellaneous - Varia
XXXVIII.c Antiphospholipid antibodies w/wo the APL syndrome
I.a
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
I.e
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.e Bradycardia
I.f
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.f Tachycardia
I.j
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.j Asystole
I.l
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.l Cardiac- cardiorespiratory/pulmonary arrest
II.d
II. Myocardial dysfunction - Heart failure
II.d Cardiovascular collapse - Cardiogenic shock - Hypotension
IV.a
IV. Heart block (bundle branch-, AV-block)
IV.a Heart block (bundle branch- or AV-)
V.a
V. Myocarditis
V.a Myocarditis (can be fulminate/fulminant)
V.b
V. Myocarditis
V.b Eosinophilic myocarditis
VI.a
VI. Cardiomyopathy
VI.a Cardiomyopathy (acute, subacute, chronic)
VII.a
VII. Cardiotoxicity
VII.a ‘Cardiotoxicity’
VII.b
VII. Cardiotoxicity
VII.b Veterinary: Cardiotoxicity
XIV.a
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XVI.e
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXII.b
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
I.a
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
I.e
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.e Bradycardia
I.g
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.g QTc prolongation
I.i
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.i Torsades de pointe
I.l
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.l Cardiac- cardiorespiratory/pulmonary arrest
IV.a
IV. Heart block (bundle branch-, AV-block)
IV.a Heart block (bundle branch- or AV-)
VI.c
VI. Cardiomyopathy
VI.c Takotsubo (stress) cardiomyopathy
VII.a
VII. Cardiotoxicity
VII.a ‘Cardiotoxicity’
XXII.e
XXII. Acute respiratory/cardiorespiratory failure
XXII.e Respiratory failure from ventilatory depression (of neuromuscular cause or causes)
XXXVI.f
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)
XXXVIII.d
XXXVIII. Miscellaneous - Varia
XXXVIII.d Death following exposure or poisoning
I.e
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.e Bradycardia
X.b
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XXIX.a
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXIX.k
XXIX. Small airway involvement
XXIX.k Cough, acute (can be violent and/or explosive)
I.e
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.e Bradycardia
II.d
II. Myocardial dysfunction - Heart failure
II.d Cardiovascular collapse - Cardiogenic shock - Hypotension
X.h
X. Pulmonary edema
X.h Negative pressure pulmonary edema (NPPE)
XXVIII.a
XXVIII. Large airway involvement
XXVIII.a Angioedema (may cause UAO, asphyxia and death)
XXVIII.f
XXVIII. Large airway involvement
XXVIII.f Laryngospasm (a.k.a. laryngismus)
XXIX.a
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXIX.c
XXIX. Small airway involvement
XXIX.c Severe or catastrophic bronchospasm or asthma attack (can be fatal)
XXIX.d
XXIX. Small airway involvement
XXIX.d Cough (lone)
XXXVI.f
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)