The Drug-Induced Respiratory Disease Website

XI. Pulmonary vasculopathies

XI.a Pulmonary arterial hypertension

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XIV. Pleural involvement

XIV.b Massive pleural effusion

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.k Pulmonary infiltrates

XXII. Acute respiratory/cardiorespiratory failure

XXII.e Respiratory failure from ventilatory depression (of neuromuscular cause or causes)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.c Hematoma of/around central airway wall potentially causing UAO

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.h Coagulopathy

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.i Hemoptysis

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.f Tachycardia

III. Myocardial ischemia - Coronary artery disease

III.a Coronary artery disease (acute) - Myocardial ischemia/infarction

XXVIII. Large airway involvement

XXVIII.a Angioedema (may cause UAO, asphyxia and death)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome

XI. Pulmonary vasculopathies

XI.a Pulmonary arterial hypertension

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

XXXVIII. Miscellaneous - Varia

XXXVIII.e Sniffing death - Death from inhalation of compound

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.f Tachycardia

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.g QTc prolongation

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.l Cardiac- cardiorespiratory/pulmonary arrest

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

II. Myocardial dysfunction - Heart failure

II.c Heart failure (biventricular, congestive)

II. Myocardial dysfunction - Heart failure

II.d Cardiovascular collapse - Cardiogenic shock - Hypotension

II. Myocardial dysfunction - Heart failure

II.e Acute respiratory or cardiopulmonary failure

III. Myocardial ischemia - Coronary artery disease

III.c Coronary vasospasm - Vasospastic angina

III. Myocardial ischemia - Coronary artery disease

III.g ST segment changes

VI. Cardiomyopathy

VI.a Cardiomyopathy (acute, subacute, chronic)

VII. Cardiotoxicity

VII.a ‘Cardiotoxicity’

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

X. Pulmonary edema

X.c Interstitial pulmonary edema

XII. Pericardial involvement

XII.b Pericardial effusion (w/wo tamponade)

XIII. Thrombosis - Embolism

XIII.a Pulmonary embolism - Venous thrombosis/thrombo-embolism

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.i Hemoptysis

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.k Pulmonary infiltrates

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.y Cytokine release syndrome

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

II. Myocardial dysfunction - Heart failure

II.c Heart failure (biventricular, congestive)

VI. Cardiomyopathy

VI.a Cardiomyopathy (acute, subacute, chronic)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.j Major/massive hemoptysis

II. Myocardial dysfunction - Heart failure

II.e Acute respiratory or cardiopulmonary failure

XXXVIII. Miscellaneous - Varia

XXXVIII.m Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

II. Myocardial dysfunction - Heart failure

II.d Cardiovascular collapse - Cardiogenic shock - Hypotension

III. Myocardial ischemia - Coronary artery disease

III.a Coronary artery disease (acute) - Myocardial ischemia/infarction

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

XXXVIII. Miscellaneous - Varia

XXXVIII.d Death following exposure or poisoning

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

V. Myocarditis

V.a Myocarditis (can be fulminate/fulminant)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)