The Drug-Induced Respiratory Disease Website
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
II. Myocardial dysfunction - Heart failure
II.e Acute respiratory or cardiopulmonary failure
III. Myocardial ischemia - Coronary artery disease
III.a Coronary artery disease (acute) - Myocardial ischemia/infarction
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XIII. Thrombosis - Embolism
XIII.a Pulmonary embolism - Venous thrombosis/thrombo-embolism
XIII. Thrombosis - Embolism
XIII.o Systemic arterial thrombosis
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.h Coagulopathy
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.i Hemoptysis
XXI. Mediastinal involvement/injury
XXI.c Pneumomediastinum
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXII. Acute respiratory/cardiorespiratory failure
XXII.e Respiratory failure from ventilatory depression (of neuromuscular cause or causes)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.d Acute eosinophilic pneumonia (AEP)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.k Pulmonary infiltrates
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.w Aspiration, aspiration pneumonia (w/wo demonstrable pharyngeal dysmotility)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.k Multiple organ dysfunction/failure (MODS/MOF)
XXXVIII. Miscellaneous - Varia
XXXVIII.d Death following exposure or poisoning
XXXVIII. Miscellaneous - Varia
XXXVIII.r Hyperemesis
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.p Oropharyngeal erosion/bleeding
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
III. Myocardial ischemia - Coronary artery disease
III.a Coronary artery disease (acute) - Myocardial ischemia/infarction
III. Myocardial ischemia - Coronary artery disease
III.c Coronary vasospasm - Vasospastic angina
V. Myocarditis
V.a Myocarditis (can be fulminate/fulminant)
VII. Cardiotoxicity
VII.a ‘Cardiotoxicity’
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XXI. Mediastinal involvement/injury
XXI.a Lymphadenopathy (intrathoracic)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.s ILD with a granulomatous component
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.c Sarcoid-like granulomatosis (endo-/extrathoracic)
II. Myocardial dysfunction - Heart failure
II.a Left ventricular dysfunction/failure
VI. Cardiomyopathy
VI.a Cardiomyopathy (acute, subacute, chronic)
VII. Cardiotoxicity
VII.a ‘Cardiotoxicity’
XI. Pulmonary vasculopathies
XI.a Pulmonary arterial hypertension
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXXIX. Rechallenge
XXXIX.a Rechallenge can lead to near-fatal or fatal relapse of AE/ILD
XI. Pulmonary vasculopathies
XI.g Pulmonary vein stenosis
XII. Pericardial involvement
XII.k Pneumopericardium
XII. Pericardial involvement
XII.m Pericardial-esophageal fistula
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.c Hematoma of/around central airway wall potentially causing UAO
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.j Major/massive hemoptysis
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.f Tachycardia
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.j Asystole
VI. Cardiomyopathy
VI.a Cardiomyopathy (acute, subacute, chronic)
XXXVIII. Miscellaneous - Varia
XXXVIII.d Death following exposure or poisoning
XXXVIII. Miscellaneous - Varia
XXXVIII.q Myopathy-Myositis-Polymyositis
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.l Cardiac- cardiorespiratory/pulmonary arrest
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.n Respiratory arrest - Apnea
XI. Pulmonary vasculopathies
XI.a Pulmonary arterial hypertension
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)