The Drug-Induced Respiratory Disease Website

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.c Ventricular tachycardia

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.l Cardiac- cardiorespiratory/pulmonary arrest

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

XXXVIII. Miscellaneous - Varia

XXXVIII.d Death following exposure or poisoning

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.l Cardiac- cardiorespiratory/pulmonary arrest

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

X. Pulmonary edema

X.d Fluid retention

X. Pulmonary edema

X.f Capillary leak syndrome (CLS)

XII. Pericardial involvement

XII.b Pericardial effusion (w/wo tamponade)

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.q Tumor lysis syndrome (TLS)

XXXVIII. Miscellaneous - Varia

XXXVIII.k Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

IV. Heart block (bundle branch-, AV-block)

IV.a Heart block (bundle branch- or AV-)

VI. Cardiomyopathy

VI.a Cardiomyopathy (acute, subacute, chronic)

VII. Cardiotoxicity

VII.a ‘Cardiotoxicity’

VII. Cardiotoxicity

VII.b Veterinary: Cardiotoxicity

IX. Endocardial involvement

IX.b Endocardial fibroelastosis

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXXII. Esophageal pathology

XXXII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula, Boerhaave’s syndrome)

XXIII. Hemoglobinopathies (acquired, reversible)

XXIII.a Methemoglobinemia

XXXVII. Veterinary medicine and pathology

XXXVII.f Veterinary: Methemoglobinemia

XIV. Pleural involvement

XIV.d Eosinophilic pleural effusion

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.c Sarcoid-like granulomatosis (endo-/extrathoracic)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.j Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

V. Myocarditis

V.a Myocarditis (can be fulminate/fulminant)

XII. Pericardial involvement

XII.b Pericardial effusion (w/wo tamponade)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXX. Imaging features

XXX.j Imaging: Bronchiectasis

XXX. Imaging features

XXX.k Imaging: Centrilobular micronodules (can be diffuse)

XXXIII. Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)

XXXIII.a Path: Myocarditis

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.h Myasthenia gravis - Myasthenic-like syndrome

XXXVIII. Miscellaneous - Varia

XXXVIII.q Myopathy-Myositis-Polymyositis

XIII. Thrombosis - Embolism

XIII.a Pulmonary embolism - Venous thrombosis/thrombo-embolism

XXIII. Hemoglobinopathies (acquired, reversible)

XXIII.a Methemoglobinemia