The Drug-Induced Respiratory Disease Website
II. Myocardial dysfunction - Heart failure
II.d Cardiovascular collapse - Cardiogenic shock - Hypotension
II. Myocardial dysfunction - Heart failure
II.f Myocardial stunning
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
X. Pulmonary edema
X.e Overload pulmonary edema (including posttransfusional (TACO))
X. Pulmonary edema
X.k Transfusion-related acute lung injury (TRALI) (May cause ARDS)
XI. Pulmonary vasculopathies
XI.b Acute pulmonary hypertension
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.f Diffuse alveolar damage (DAD) imaging pattern
XXVIII. Large airway involvement
XXVIII.a Angioedema (may cause UAO, asphyxia and death)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.e Bradycardia
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.f Tachycardia
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.j Asystole
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.l Cardiac- cardiorespiratory/pulmonary arrest
II. Myocardial dysfunction - Heart failure
II.d Cardiovascular collapse - Cardiogenic shock - Hypotension
IV. Heart block (bundle branch-, AV-block)
IV.a Heart block (bundle branch- or AV-)
V. Myocarditis
V.a Myocarditis (can be fulminate/fulminant)
V. Myocarditis
V.b Eosinophilic myocarditis
VI. Cardiomyopathy
VI.a Cardiomyopathy (acute, subacute, chronic)
VII. Cardiotoxicity
VII.a ‘Cardiotoxicity’
VII. Cardiotoxicity
VII.b Veterinary: Cardiotoxicity
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.l Acute fibrinous organizing pneumonia (AFOP)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.y Exogenous lipoid pneumonia (subacute, acute)
XXXIII. Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)
XXXIII.y Path: Acute fibrinous organizing pneumonia (AFOP) pattern (see also If)
XXII. Acute respiratory/cardiorespiratory failure
XXII.a Respiratory distress or failure, not otherwise specified
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXVIII. Large airway involvement
XXVIII.g Thermal (burns, frostbite), chemical or caustic injury (face, buccal mucosa, pharynx, upper airway)
XXIX. Small airway involvement
XXIX.e Obliterative bronchiolitis (an imaging and/or pathological pattern consistent with)
XXXII. Esophageal pathology
XXXII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula, Boerhaave’s syndrome)
XXXII. Esophageal pathology
XXXII.g Esophageal stenosis/stricture
XII. Pericardial involvement
XII.b Pericardial effusion (w/wo tamponade)
XII. Pericardial involvement
XII.e Constrictive pericarditis - Pericardial thickening
XII. Pericardial involvement
XII.g Pleural/pericardial effusion, ANA positive (DI lupus)
XII. Pericardial involvement
XII.n Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)
XV. Chest pain
XV.e Pleuritis (can cause chest pain)
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.g Alveolar hemorrhage, diffuse (ANCA-positive/-related)
XX. Vasculitis
XX.c Vascultis (pulmonary, extrathoracic or systemic) - ANCA status unknown or negative
XX. Vasculitis
XX.d Vasculitis, pulmonary (w/wo AH), extrathoracic, or systemic: ANCA-positive
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)
XXVIII. Large airway involvement
XXVIII.a Angioedema (may cause UAO, asphyxia and death)
XXVIII. Large airway involvement
XXVIII.d Vocal cord dysfunction, adduction, closure
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXIX. Small airway involvement
XXIX.b Occupational asthma
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.a Autoimmunity - An autoimmune condition (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.b Lupus - Lupus syndrome
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.s Dual MPO-/PR3-ANCA systemic disease/vasculitis or pseudovasculitis
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.t Pneumorenal syndrome (w/wo ANCAs)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.u Pulmonary vasculitis or capillaritis
XXXVIII. Miscellaneous - Varia
XXXVIII.a Upper airway obstruction other than angioedema or hematoma
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.g QTc prolongation
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.i Torsades de pointe
II. Myocardial dysfunction - Heart failure
II.a Left ventricular dysfunction/failure
IV. Heart block (bundle branch-, AV-block)
IV.a Heart block (bundle branch- or AV-)
VI. Cardiomyopathy
VI.a Cardiomyopathy (acute, subacute, chronic)
XI. Pulmonary vasculopathies
XI.a Pulmonary arterial hypertension
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXXIII. Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)
XXXIII.e Path: Lysosomal storage cardiomyopathy/cardiotoxicity