The Drug-Induced Respiratory Disease Website
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXII. Acute respiratory/cardiorespiratory failure
XXII.c Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.ag Chemical (toxic) pneumonitis
II. Myocardial dysfunction - Heart failure
II.a Left ventricular dysfunction/failure
II. Myocardial dysfunction - Heart failure
II.d Cardiovascular collapse - Cardiogenic shock - Hypotension
III. Myocardial ischemia - Coronary artery disease
III.a Coronary artery disease (acute) - Myocardial ischemia/infarction
V. Myocarditis
V.a Myocarditis (can be fulminate/fulminant)
V. Myocarditis
V.b Eosinophilic myocarditis
V. Myocarditis
V.f Myopericarditis
X. Pulmonary edema
X.a Pulmonary edema, cardiogenic
XII. Pericardial involvement
XII.a Pericarditis
XII. Pericardial involvement
XII.b Pericardial effusion (w/wo tamponade)
XII. Pericardial involvement
XII.n Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV. Pleural involvement
XIV.d Eosinophilic pleural effusion
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.d Acute eosinophilic pneumonia (AEP)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.p An area or areas of consolidation
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.s ILD with a granulomatous component
XXVIII. Large airway involvement
XXVIII.m Bronchiectasis
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.b Lupus - Lupus syndrome
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.g QTc prolongation
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.i Torsades de pointe
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.n Respiratory arrest - Apnea
II. Myocardial dysfunction - Heart failure
II.b Right ventricular dysfunction/failure
VI. Cardiomyopathy
VI.c Takotsubo (stress) cardiomyopathy
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XI. Pulmonary vasculopathies
XI.a Pulmonary arterial hypertension
XIII. Thrombosis - Embolism
XIII.k Foreign body pulmonary vasculopathy (Excipient lung disease)
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXII. Acute respiratory/cardiorespiratory failure
XXII.e Respiratory failure from ventilatory depression (of neuromuscular cause or causes)
XXII. Acute respiratory/cardiorespiratory failure
XXII.f Rigid chest syndrome - Chest wall rigidity - Stiff/wooden chest
XXXV. Disordered breathing during sleep
XXXV.b Disordered breathing pattern - Cheynes-Stokes respiration
XXXVIII. Miscellaneous - Varia
XXXVIII.d Death following exposure or poisoning
XXXVIII. Miscellaneous - Varia
XXXVIII.h Hypoxemia, low oxygen saturation (may occur in isolation)
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.m Sudden cardiac death
II. Myocardial dysfunction - Heart failure
II.e Acute respiratory or cardiopulmonary failure
III. Myocardial ischemia - Coronary artery disease
III.a Coronary artery disease (acute) - Myocardial ischemia/infarction
VI. Cardiomyopathy
VI.a Cardiomyopathy (acute, subacute, chronic)
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XI. Pulmonary vasculopathies
XI.a Pulmonary arterial hypertension
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XX. Vasculitis
XX.c Vascultis (pulmonary, extrathoracic or systemic) - ANCA status unknown or negative
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.k Multiple organ dysfunction/failure (MODS/MOF)
XXXVIII. Miscellaneous - Varia
XXXVIII.d Death following exposure or poisoning
XXXVIII. Miscellaneous - Varia
XXXVIII.s CNS involvement/dysfunction/damage
II. Myocardial dysfunction - Heart failure
II.e Acute respiratory or cardiopulmonary failure
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXXVIII. Miscellaneous - Varia
XXXVIII.m Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XXIII. Hemoglobinopathies (acquired, reversible)
XXIII.a Methemoglobinemia
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)
XXXVIII. Miscellaneous - Varia
XXXVIII.g Bluish, blue, pseudocyanotic skin discoloration
XXXVIII. Miscellaneous - Varia
XXXVIII.m Metabolic acidosis (incl. lactic acidosis/-gap). May cause hyperpnea/dyspnea
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome