The Drug-Induced Respiratory Disease Website

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

VII. Cardiotoxicity

VII.a ‘Cardiotoxicity’

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

X. Pulmonary edema

X.d Fluid retention

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

II. Myocardial dysfunction - Heart failure

II.d Cardiovascular collapse - Cardiogenic shock - Hypotension

III. Myocardial ischemia - Coronary artery disease

III.a Coronary artery disease (acute) - Myocardial ischemia/infarction

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

XXXVIII. Miscellaneous - Varia

XXXVIII.d Death following exposure or poisoning

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

X. Pulmonary edema

X.c Interstitial pulmonary edema

X. Pulmonary edema

X.g Flash (fulminate) pulmonary edema

XXXVIII. Miscellaneous - Varia

XXXVIII.h Hypoxemia, low oxygen saturation (may occur in isolation)

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

X. Pulmonary edema

X.e Overload pulmonary edema (including posttransfusional (TACO))

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.l Cardiac- cardiorespiratory/pulmonary arrest

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

III. Myocardial ischemia - Coronary artery disease

III.a Coronary artery disease (acute) - Myocardial ischemia/infarction

V. Myocarditis

V.a Myocarditis (can be fulminate/fulminant)

V. Myocarditis

V.b Eosinophilic myocarditis

V. Myocarditis

V.f Myopericarditis

V. Myocarditis

V.h Relapse of previously diagnosed myocarditis

VI. Cardiomyopathy

VI.c Takotsubo (stress) cardiomyopathy

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

XI. Pulmonary vasculopathies

XI.a Pulmonary arterial hypertension

XI. Pulmonary vasculopathies

XI.j Pulmonary infarction

XII. Pericardial involvement

XII.a Pericarditis

XII. Pericardial involvement

XII.b Pericardial effusion (w/wo tamponade)

XII. Pericardial involvement

XII.e Constrictive pericarditis - Pericardial thickening

XIII. Thrombosis - Embolism

XIII.a Pulmonary embolism - Venous thrombosis/thrombo-embolism

XV. Chest pain

XV.a Chest pain (acute or subacute), lone or prominent

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.h Coagulopathy

XX. Vasculitis

XX.c Vascultis (pulmonary, extrathoracic or systemic) - ANCA status unknown or negative

XX. Vasculitis

XX.d Vasculitis, pulmonary (w/wo AH), extrathoracic, or systemic: ANCA-positive

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.i Progression, acceleration or exacerbation of preexisting ILD/fibrosis

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.v Radiation recall pneumonitis

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXIX. Small airway involvement

XXIX.h Exacerbation or deterioration of preexisting asthma

XXX. Imaging features

XXX.l Imaging: Ground-glass opacities / GGO shadowing

XXX. Imaging features

XXX.p Imaging: Asymmetrical, predominantly unilateral involvement

XXX. Imaging features

XXX.s Imaging: A mosaic pattern of attenuation

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.b Lupus - Lupus syndrome

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.i Guillain-Barré (or GB-like) syndrome (w/wo ARF)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.j Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.n A flare of preexisting immune-mediated systemic/rheumatic disease

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.x Anti Jo1 syndrome

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.z Protracted, prolonged anaphylaxis

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.ae Polyarteritis nodosa-like condition

XXXVIII. Miscellaneous - Varia

XXXVIII.c Antiphospholipid antibodies w/wo the APL syndrome

XXXVIII. Miscellaneous - Varia

XXXVIII.q Myopathy-Myositis-Polymyositis

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

II. Myocardial dysfunction - Heart failure

II.d Cardiovascular collapse - Cardiogenic shock - Hypotension

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

X. Pulmonary edema

X.h Negative pressure pulmonary edema (NPPE)

X. Pulmonary edema

X.m Neurogenic pulmonary edema

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)

III. Myocardial ischemia - Coronary artery disease

III.a Coronary artery disease (acute) - Myocardial ischemia/infarction

VI. Cardiomyopathy

VI.a Cardiomyopathy (acute, subacute, chronic)

VII. Cardiotoxicity

VII.a ‘Cardiotoxicity’

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

XII. Pericardial involvement

XII.b Pericardial effusion (w/wo tamponade)

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIII. Hemoglobinopathies (acquired, reversible)

XXIII.a Methemoglobinemia

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXIX. Small airway involvement

XXIX.c Severe or catastrophic bronchospasm or asthma attack (can be fatal)

XXX. Imaging features

XXX.o Imaging: Lung nodule or nodules

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.c Sarcoid-like granulomatosis (endo-/extrathoracic)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

II. Myocardial dysfunction - Heart failure

II.a Left ventricular dysfunction/failure

VI. Cardiomyopathy

VI.a Cardiomyopathy (acute, subacute, chronic)

X. Pulmonary edema

X.a Pulmonary edema, cardiogenic

XII. Pericardial involvement

XII.b Pericardial effusion (w/wo tamponade)

XII. Pericardial involvement

XII.r Chylous pericardial effusion (w/wo tamponade)

XIV. Pleural involvement

XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)