The Drug-Induced Respiratory Disease Website

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.l Cardiac- cardiorespiratory/pulmonary arrest

X. Pulmonary edema

X.b Pulmonary edema, noncardiogenic (NCPE)

X. Pulmonary edema

X.d Fluid retention

XIII. Thrombosis - Embolism

XIII.f Fat/oil embolism - The FES embolism syndrome

XV. Chest pain

XV.a Chest pain (acute or subacute), lone or prominent

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXXIII. Histopathology (for pulmonary pathology see in ‘Pneumotox’ (a free companion App)

XXXIII.o Path: Lipid/fat embolism

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma

XXXVIII. Miscellaneous - Varia

XXXVIII.k Hypersensitivity reaction (may manifest with fever and/or skin, throat or airway involvement)

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.l Cardiac- cardiorespiratory/pulmonary arrest

XXII. Acute respiratory/cardiorespiratory failure

XXII.a Respiratory distress or failure, not otherwise specified

XXVIII. Large airway involvement

XXVIII.d Vocal cord dysfunction, adduction, closure

XXVIII. Large airway involvement

XXVIII.f Laryngospasm (a.k.a. laryngismus)

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.n Respiratory arrest - Apnea

XXII. Acute respiratory/cardiorespiratory failure

XXII.a Respiratory distress or failure, not otherwise specified

XXII. Acute respiratory/cardiorespiratory failure

XXII.e Respiratory failure from ventilatory depression (of neuromuscular cause or causes)

XXII. Acute respiratory/cardiorespiratory failure

XXII.g Respiratory acidosis - Hypercapnia - Elevated blood CO2

XXIX. Small airway involvement

XXIX.f Deterioration/exacerbation of preexisting asthma or COPD

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma

XXXVIII. Miscellaneous - Varia

XXXVIII.d Death following exposure or poisoning

XXXVIII. Miscellaneous - Varia

XXXVIII.n Hiccup

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma

XII. Pericardial involvement

XII.b Pericardial effusion (w/wo tamponade)

XII. Pericardial involvement

XII.e Constrictive pericarditis - Pericardial thickening

XII. Pericardial involvement

XII.g Pleural/pericardial effusion, ANA positive (DI lupus)

XII. Pericardial involvement

XII.n Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)

XV. Chest pain

XV.e Pleuritis (can cause chest pain)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)

XVI. Hemorrhage - Bleeding - Hematoma(s)

XVI.g Alveolar hemorrhage, diffuse (ANCA-positive/-related)

XX. Vasculitis

XX.c Vascultis (pulmonary, extrathoracic or systemic) - ANCA status unknown or negative

XX. Vasculitis

XX.d Vasculitis, pulmonary (w/wo AH), extrathoracic, or systemic: ANCA-positive

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.a Pneumonitis (ILD)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)

XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis

XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)

XXVIII. Large airway involvement

XXVIII.a Angioedema (may cause UAO, asphyxia and death)

XXVIII. Large airway involvement

XXVIII.d Vocal cord dysfunction, adduction, closure

XXIX. Small airway involvement

XXIX.a Bronchospasm - Wheezing - Asthma

XXIX. Small airway involvement

XXIX.b Occupational asthma

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.a Autoimmunity - An autoimmune condition (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.b Lupus - Lupus syndrome

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.s Dual MPO-/PR3-ANCA systemic disease/vasculitis or pseudovasculitis

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.t Pneumorenal syndrome (w/wo ANCAs)

XXXVI. Autoimmune syndromes - Systemic reactions or conditions

XXXVI.u Pulmonary vasculitis or capillaritis

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma

XXII. Acute respiratory/cardiorespiratory failure

XXII.a Respiratory distress or failure, not otherwise specified

XXII. Acute respiratory/cardiorespiratory failure

XXII.e Respiratory failure from ventilatory depression (of neuromuscular cause or causes)

XXVIII. Large airway involvement

XXVIII.g Thermal (burns, frostbite), chemical or caustic injury (face, buccal mucosa, pharynx, upper airway)

XXXII. Esophageal pathology

XXXII.b Esophageal pathology (erosion, ulcer, tear, rupture, fistula, Boerhaave’s syndrome)

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma

I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)

I.k Sinus arrest

IV. Heart block (bundle branch-, AV-block)

IV.a Heart block (bundle branch- or AV-)

V. Myocarditis

V.a Myocarditis (can be fulminate/fulminant)

VII. Cardiotoxicity

VII.a ‘Cardiotoxicity’

XXII. Acute respiratory/cardiorespiratory failure

XXII.b Acute lung injury - ARDS

XXXVIII. Miscellaneous - Varia

XXXVIII.a Upper airway obstruction other than angioedema or hematoma