Philippe Camus, M.D.
Dijon, France
XXIV - Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
Last update 17/06/2026
(Fr. atteinte infraclinique). Interstitial or alveolar opacities detected incidentally on HRCT or if the BAL shows increased lymphocytes, neutrophils or eosinophils. PFTs typically yield normal results. See also under Iv
XII. Pericardial involvement
XII.b Pericardial effusion (w/wo tamponade)
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.k Pulmonary infiltrates
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.m Subclinical pulmonary infiltrates/ILD
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
VI. Cardiomyopathy
VI.c Takotsubo (stress) cardiomyopathy
XI. Pulmonary vasculopathies
XI.b Acute pulmonary hypertension
XII. Pericardial involvement
XII.g Pleural/pericardial effusion, ANA positive (DI lupus)
XIII. Thrombosis - Embolism
XIII.a Pulmonary embolism - Venous thrombosis/thrombo-embolism
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV. Pleural involvement
XIV.h Pleural thickening - Fibrothorax
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.i Hemoptysis
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXII. Acute respiratory/cardiorespiratory failure
XXII.d Postoperative ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.d Acute eosinophilic pneumonia (AEP)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.e Relapsing or migrating pneumonitis/pneumonia (see also Id)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.f Diffuse alveolar damage (DAD) imaging pattern
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.g Amiodarone pulmonary toxicity - Amiodarone lung
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.h Pulmonary fibrosis (may improve but partly following drug discontinuation)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.k Pulmonary infiltrates
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.l Acute fibrinous organizing pneumonia (AFOP)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.m Subclinical pulmonary infiltrates/ILD
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.n A mass or masses
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.o Rapidly progressive ILD/pulmonary fibrosis (Hamman-Rich syndrome)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.p An area or areas of consolidation
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.q Delayed ILD, -pneumonitis, -fibrosis
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.r Lung nodule or nodules
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.z Unilateral interstitial lung disease
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.ab Chronic pneumonitis/ILD
XXVI. Neuromuscular dysfunction
XXVI.d Respiratory failure (hypoxemia, acidosis) from myxedema coma
XXVIII. Large airway involvement
XXVIII.a Angioedema (may cause UAO, asphyxia and death)
XXVIII. Large airway involvement
XXVIII.h Airway pigmentation (black, bluish, petechial)
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXIX. Small airway involvement
XXIX.d Cough (lone)
XXX. Imaging features
XXX.p Imaging: Asymmetrical, predominantly unilateral involvement
XXX. Imaging features
XXX.r Imaging: Waxing and waning nodules
XXXI. Eye catchers
XXXI.f Eye-catcher: An electron-dense liver on unenhanced CT
XXXI. Eye catchers
XXXI.g Eye-catcher: An electron-dense ('white') thyroid
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.b Lupus - Lupus syndrome
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.p Multisystem/systemic inflammatory response/syndrome
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.g QTc prolongation
II. Myocardial dysfunction - Heart failure
II.c Heart failure (biventricular, congestive)
VII. Cardiotoxicity
VII.a ‘Cardiotoxicity’
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.m Subclinical pulmonary infiltrates/ILD
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.u Transient pulmonary opacities/infiltrates (TAPO)
XXXIX. Rechallenge
XXXIX.a Rechallenge can lead to near-fatal or fatal relapse of AE/ILD
XXXIX. Rechallenge
XXXIX.e Rechallenge may not lead to relapse of the AE/ILD
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.m Subclinical pulmonary infiltrates/ILD
V. Myocarditis
V.a Myocarditis (can be fulminate/fulminant)
XII. Pericardial involvement
XII.e Constrictive pericarditis - Pericardial thickening
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.m Subclinical pulmonary infiltrates/ILD
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.b Lupus - Lupus syndrome
