Philippe Camus, M.D.
Dijon, France
XIV - Pleural involvement
Last update 17/06/2026
(Pleural eosinophilie >10%). Peripheral eosinophilia, eosinophilic pleuritis, eosinophilic pneumonia and/or BAL eosinophilia can be present as associated features. See PMID 10424528, 12806236
XII. Pericardial involvement
XII.g Pleural/pericardial effusion, ANA positive (DI lupus)
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV. Pleural involvement
XIV.d Eosinophilic pleural effusion
XIX. Angioedema
XIX.b Visceral angioedema
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXVIII. Large airway involvement
XXVIII.a Angioedema (may cause UAO, asphyxia and death)
XXVIII. Large airway involvement
XXVIII.i Tongue involvement (edema, glossitis, hematoma)
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXIX. Small airway involvement
XXIX.c Severe or catastrophic bronchospasm or asthma attack (can be fatal)
XXIX. Small airway involvement
XXIX.d Cough (lone)
XXX. Imaging features
XXX.c Imaging: Upper/central airway narrowing
XXXI. Eye catchers
XXXI.a Eye-catcher: Tongue edema
XXXV. Disordered breathing during sleep
XXXV.b Disordered breathing pattern - Cheynes-Stokes respiration
XXXV. Disordered breathing during sleep
XXXV.c Obstructive sleep apnea
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.b Lupus - Lupus syndrome
XXXVIII. Miscellaneous - Varia
XXXVIII.b Unilateral/Hemilingual (angio)edema
XXXVIII. Miscellaneous - Varia
XXXVIII.i Cough syncope
XIII. Thrombosis - Embolism
XIII.c Cement embolism
XIII. Thrombosis - Embolism
XIII.e Cyanoacrylate pulmonary embolism
XIV. Pleural involvement
XIV.d Eosinophilic pleural effusion
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXXI. Eye catchers
XXXI.b Eye-catcher: Cement (pulmonary) embolism
XIV. Pleural involvement
XIV.d Eosinophilic pleural effusion
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.c Sarcoid-like granulomatosis (endo-/extrathoracic)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.j Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)
XIV. Pleural involvement
XIV.d Eosinophilic pleural effusion
XIX. Angioedema
XIX.b Visceral angioedema
XXVIII. Large airway involvement
XXVIII.a Angioedema (may cause UAO, asphyxia and death)
XXVIII. Large airway involvement
XXVIII.f Laryngospasm (a.k.a. laryngismus)
XXVIII. Large airway involvement
XXVIII.i Tongue involvement (edema, glossitis, hematoma)
XXIX. Small airway involvement
XXIX.d Cough (lone)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.b Lupus - Lupus syndrome
II. Myocardial dysfunction - Heart failure
II.a Left ventricular dysfunction/failure
II. Myocardial dysfunction - Heart failure
II.d Cardiovascular collapse - Cardiogenic shock - Hypotension
III. Myocardial ischemia - Coronary artery disease
III.a Coronary artery disease (acute) - Myocardial ischemia/infarction
V. Myocarditis
V.a Myocarditis (can be fulminate/fulminant)
V. Myocarditis
V.b Eosinophilic myocarditis
V. Myocarditis
V.f Myopericarditis
X. Pulmonary edema
X.a Pulmonary edema, cardiogenic
XII. Pericardial involvement
XII.a Pericarditis
XII. Pericardial involvement
XII.b Pericardial effusion (w/wo tamponade)
XII. Pericardial involvement
XII.n Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV. Pleural involvement
XIV.d Eosinophilic pleural effusion
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.d Acute eosinophilic pneumonia (AEP)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.p An area or areas of consolidation
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.s ILD with a granulomatous component
XXVIII. Large airway involvement
XXVIII.m Bronchiectasis
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.b Lupus - Lupus syndrome
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.n Respiratory arrest - Apnea
X. Pulmonary edema
X.b Pulmonary edema, noncardiogenic (NCPE)
XII. Pericardial involvement
XII.g Pleural/pericardial effusion, ANA positive (DI lupus)
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV. Pleural involvement
XIV.d Eosinophilic pleural effusion
XV. Chest pain
XV.a Chest pain (acute or subacute), lone or prominent
XV. Chest pain
XV.b Pleuritic chest pain
XV. Chest pain
XV.e Pleuritis (can cause chest pain)
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.c Hematoma of/around central airway wall potentially causing UAO
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXI. Mediastinal involvement/injury
XXI.a Lymphadenopathy (intrathoracic)
XXII. Acute respiratory/cardiorespiratory failure
XXII.b Acute lung injury - ARDS
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.d Acute eosinophilic pneumonia (AEP)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.f Diffuse alveolar damage (DAD) imaging pattern
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.h Pulmonary fibrosis (may improve but partly following drug discontinuation)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.j Organizing pneumonia (OP/BOOP) pattern (an area or areas of consolidation on imaging)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.ab Chronic pneumonitis/ILD
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.ah Transient pulmonary opacities/infiltrates (see also under Iav)
XXV. Pulmonary function - Pulmonary physiology - PFTs
XXV.i A restrictive lung function defect
XXVIII. Large airway involvement
XXVIII.o A ‘tracheobronchitis’ clinical pattern
XXIX. Small airway involvement
XXIX.a Bronchospasm - Wheezing - Asthma
XXX. Imaging features
XXX.u Imaging: Reverse ventilation-perfusion mismatch
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.a Autoimmunity - An autoimmune condition (+ANA, +anti-ds-DNA, +ANCAs, other auto-Abs)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.b Lupus - Lupus syndrome
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.f Anaphylaxis - Anaphylactoid reaction (either of these can be fatal)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.u Pulmonary vasculitis or capillaritis
I. Cardiac arrhythmia(s)/dysrhythmia(s) (AF, VT, VF, TdP) - QTc prolongation)
I.a Cardiac arrhythmias or dysrhythmias (AF, VT, VF, TdP)
XII. Pericardial involvement
XII.g Pleural/pericardial effusion, ANA positive (DI lupus)
XII. Pericardial involvement
XII.n Pleuropericarditis - Pleuropericardial effusion (ANA unknown or negative)
XIV. Pleural involvement
XIV.a Pleural effusion (uni or bilateral) (can accompany ILD induced by the drug)
XIV. Pleural involvement
XIV.d Eosinophilic pleural effusion
XVI. Hemorrhage - Bleeding - Hematoma(s)
XVI.e Alveolar hemorrhage (AH), diffuse AH (DAH)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.a Pneumonitis (ILD)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.b Pneumonitis (ILD), acute and/or severe (may cause ARDS)
XXIV. Interstitial lung disease - Pulmonary infiltrates - Pulmonary fibrosis
XXIV.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)
XXXVI. Autoimmune syndromes - Systemic reactions or conditions
XXXVI.m DRES syndrome - DRESS-like reaction - Drug hypersensitivity syndrome
